Key Players and Innovative Start-ups in Nutraceuticals
Emerging strategies in ingredients, pharma, food and drinks
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| Overview: | |
| Nutraceuticals are bioactive compounds with properties beneficial to health that are often concentrated extracts from fruits, herbs, seeds, specific lipids and vegetables. Nutraceuticals are often used to fortify food products, creating functional foods, or can be taken as supplements. Pharmaceuticals, on the other hand, are bioactive compounds intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease. Pharmaceuticals are most often new chemical entities. Over the past few years, most of nutraceutical ingredients have made good progress in the marketplace and are now available in a wide range of foods and drinks, as well as supplements. Some have also been developed as pharmaceuticals. The consumer environment is driving growth in the nutraceuticals market. Over the past decade, consumers have become more concerned for their health and are increasingly inclined to self-medicate. Healthcare providers, too, are keen to shift some of the burden of healthcare costs to individuals and recognize that functional foods may provide alternatives to medications. These factors are reflected in the current market for ingredients in the health and nutrition sector, which was estimated to be worth US$4 billion in 2009. This report reviews the strategies of leading companies within different sectors of the nutraceuticals market. It also identifies new entrants to the market that are bringing biotech tools to the discovery and development of new ingredients with health benefits. | |
| Keywords: Antioxidants, epigenetics, finished goods, medicalization, nanotechnology, Nutraceutical, nutrigenetics, nutrigenomics, omega-3, prebiotics, probiotics, raw materials, regulation, stanols, sterols | |
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By Dr Cheryl L Barton / Publication Date: 2nd November 2009
Contents:
Executive summary 10
Defining nutraceuticals 10
Market leaders: food and drinks manufacturers 11
Market leaders: ingredients 12
Market leaders: pharmaceutical companies 13
Developing new ingredients: innovative start-up companies 14
Market drivers and trends 15
Chapter 1 Defining nutraceuticals 18
Summary 18
Introduction 19
Defining nutraceuticals 20
Examples of nutraceuticals 22
Omega-3 oils 24
Probiotics 25
Prebiotics 28
Plant stanols and sterols 29
Superfruits and antioxidants 30
The nutraceuticals market 31
Report outline 34
Chapter 2 Market leaders: Food and drinks
companies 38
Summary 38
Introduction 39
Market Leaders: Case studies 40
Case study: Nestlé 40
Case study: Unilever 46
Case study: Groupe Danone 50
Case study: PepsiCo 54
Case study: Coca-Cola 56
Conclusions 58
Chapter 3 Market leaders: Ingredients 62
Summary 62
Introduction 63
Companies with diverse nutraceutical portfolios 64
Case study: DSM Nutritionals 64
Case study: Cognis 68
Case study: Cargill Inc 70
Case study: Ajinomoto 72
Case study: Kerry Group 74
Case study: Glanbia Foods 76
Probiotics 79
Case study: Chr. Hansen 79
Case study: Danisco 82
Prebiotics 85
Case study: BENEO 85
Fats and oils 87
Case study: Ocean Nutrition Canada 88
Agriculture 91
Case study: Dow AgroSciences 92
Case study: Monsanto 93
Case study: DuPont 93
Conclusions 94
Chapter 4 Market Leaders: Pharmaceutical
companies 96
Summary 96
Introduction 97
Market leaders: Case studies 99
Case Study: Abbott Nutrition 99
Case study: Bayer Consumer Care 101
Case study: Pfizer 103
Case study: GSK Consumer Healthcare 105
Case study: McNeil Nutritionals 107
Case study: Mead Johnson Nutritionals 108
Discussion 109
Chapter 5 Developing new ingredients:
Innovative start-up companies 112
Summary 112
Introduction 113
Case study: Advana Science 115
Case study: WellGen Inc 116
Case study: InterMed Discovery 118
Case study: Provexis 119
Case study: Clasado Ltd 122
Case study: Cambridge Theranostics Ltd 123
Case Study: HerbalScience Group 125
Business models 126
Conclusions 130
Chapter 6 Market drivers and trends 132
Summary 132
Introduction 133
Regulatory considerations 133
Japan 134
United States 135
Europe 137
Intellectual property 140
Development costs 141
Opportunities in the nutraceuticals market 142
Opportunities for medical foods 144
International emerging markets 146
The science driving the future foods market 148
Nutrigenomics and nutrigenetics 148
Epigenetics 148
Nanotechnology 149
Conclusions 149
Chapter 7 Appendix 152
Primary research methodology 152
Acknowledgments 152
Glossary 153
Index 156
Bibliography 158
Endnotes 163
List of Tables:
List of Tables
Table 1.1: Examples of nutraceuticals 23
Table 1.2: Omega-3 and Omega-6 fatty acids and their dietary sources 24
Table 1.3: Examples of common antioxidants present in food 30
Table 2.1: Leading food companies: revenues and product focus 39
Table 2.2: Nestlé sales by product area (CHFm), 2008 40
Table 2.3: Nestlé’s Branded Active Benefits 42
Table 2.4: Examples of brands from Nestlé Nutrition 43
Table 2.5: Functional ingredients included in Danone’s dairy products 51
Table 3.6: Market leaders: Ingredients 63
Table 3.7: Nutraceutical or personalized nutrition companies participated in by DSM Venturing
67
Table 3.8: Examples of ingredients from Danisco 83
Table 4.1: Market Leaders: Pharma 98
Table 4.2: Leading nutraceutical products from Abbott Nutrition 100
Table 4.3: Leading nutraceutical products from Bayer Consumer Care 102
Table 4.4: Leading nutritional products from Pfizer 104
Table 5.1: Innovative companies and start-ups in the nutraceutical sector 114
Table 5.2: Examples of innovative companies exploring novel manufacturing methods 115
Table 5.3: Products or projects in development at Provexis 120
Table 6.1: Health claims meeting significant scientific agreement 137
List of Figures
Figure 1.1: Different types of medical food and their uses 22
Figure 1.2: The health and nutrition sector 32
Figure 1.3: Key US consumer health concerns, 2009 33
Figure 1.4: The role of food and pharmaceuticals in the healthcare continuum 34
Figure 1.5: End products for nutraceutical ingredients 35
Figure 2.1: Danone’s sales figures by business line and sales region (2008) 50
Figure 3.1: Technologies for nutraceutical product development at Kerry Group 75
Figure 3.2: Defining Danisco’s Bioactives and Enabler ingredients 82
Figure 5.1: InterMed Discovery’s active ingredient pipeline 118
Figure 5.2: A comparison of research paradigms in the pharmaceutical and nutraceutical industries
127
Figure 5.3: Examples of business models adopted by innovative nutraceutical companies 128
Figure 6.1: Opportunities and threats for the nutraceuticals industry 133
Figure 6.2: Types of EFSA health claims 138
Figure 6.3: Key attributes for product success 143
Figure 6.4: Opportunities for medical foods 145
Figure 6.5: Growth in the number of potential consumers from developing and emerging
countries: 2008-2018 147